Hormone-relevant libido alterations in menopause tends to be charged more so you can falling testosterone membership rather than faster the hormone estrogen concentrations. 1 , six Prior to menopausal, brand new ovaries and you may adrenals create regarding 50% of distributing testosterone on the leftover 50% on the peripheral conversion process out-of precursors based on the ovary and this new adrenal gland. step 1 After menopausal, peripheral conversion process regarding androstenedione becomes the top source of distributing testosterone, though there is actually varying levels of ongoing ovarian production. 8 The brand new mean circulating quantity of testosterone declines gradually that have growing age, in place of exhibiting a great precipitous slide in the menopausal change; ergo, accounts in women aged 40 years was about half of females within their very early twenties. 8 Extremely distributing testosterone lead is bound to sex hormonal-joining globulin (SHBG) and you will albumin, making singular% so you’re able to dos% [...]